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N-Alkoxymethylation of heterocyclic compounds with diethyl phosphite via cleavage of P–O bond

Authors :
Quan, Zheng-Jun
Ren, Rong-Guo
Jia, Xiao-Dong
Da, Yu-Xia
Zhang, Zhang
Wang, Xi-Cun
Source :
Tetrahedron. Apr2011, Vol. 67 Issue 13, p2462-2467. 6p.
Publication Year :
2011

Abstract

Abstract: N-Alkoxymethylation of heterocyclic compounds with diethyl phosphite via cleavage of P–O bond was investigated and a series of N3-ethoxymethylated heterocyclic compounds were synthesized. A mechanism in which diethyl phosphite acts as an efficient surrogate of ethanol was proposed and supported by several evidences. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00404020
Volume :
67
Issue :
13
Database :
Academic Search Index
Journal :
Tetrahedron
Publication Type :
Academic Journal
Accession number :
59195020
Full Text :
https://doi.org/10.1016/j.tet.2011.01.061