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A compact result for the time-dependent probability of fixation at a neutral locus

Authors :
Waxman, D.
Source :
Journal of Theoretical Biology. Apr2011, Vol. 274 Issue 1, p131-135. 5p.
Publication Year :
2011

Abstract

Abstract: A result is derived, in the form of a sum, for the time-dependent probability of fixation of an unlinked neutral locus. The result captures many of the key features of the probability of fixation in a highly compact form. For ‘small’ times () a single term of the sum accurately determines the time-dependent probability of fixation. This is in contrast to the well-known result of Kimura, which requires the contribution of many terms in a different sum, for ‘small’ times. Going beyond small times, an approximation is derived for the time-dependent probability of fixation which applies for all times when the initial relative allele frequency is small. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00225193
Volume :
274
Issue :
1
Database :
Academic Search Index
Journal :
Journal of Theoretical Biology
Publication Type :
Academic Journal
Accession number :
58536234
Full Text :
https://doi.org/10.1016/j.jtbi.2011.01.019