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Recombinant p42[supIP4], a brain-specific 42-kDa high-affinity Ins(1,3,4,5)P[sub4] receptor protein, specifically interacts with lipid membranes containing Ptd-Ins(3,4,5)P[sub3].

Authors :
Hanck, Theodor
Stricker, Rolf
Krishna, U. Murali
Falck, John R.
Young-Tae Chang
Sung-Kee Chung
Reiser, Georg
Source :
European Journal of Biochemistry. Apr99 Part 2, Vol. 261 Issue 2, p577. 8p. 6 Diagrams, 1 Graph.
Publication Year :
1999

Abstract

Examines the cloning of the recombinant p42[sup IP4], a membrane-associated and cytosolic inositol tetrakisphosphate receptor protein. Use of protein-lipid vesicle binding assay; Analysis of the protein using Western blotting; Identification of inositol phosphates and lipids.

Subjects

Subjects :
*PROTEINS
*INOSITOL

Details

Language :
English
ISSN :
00142956
Volume :
261
Issue :
2
Database :
Academic Search Index
Journal :
European Journal of Biochemistry
Publication Type :
Academic Journal
Accession number :
5839749
Full Text :
https://doi.org/10.1046/j.1432-1327.1999.00326.x