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Seizure remission in adults with long-standing intractable epilepsy: An extended follow-up
- Source :
-
Epilepsy Research . Feb2011, Vol. 93 Issue 2/3, p115-119. 5p. - Publication Year :
- 2011
-
Abstract
- Summary: Recent studies have provided much needed data on the probability of seizure remission among adults with chronic intractable epilepsy treated medically. Here we provide an extended follow-up to our earlier study in order to provide a more comprehensive picture of long-term prognosis in this patient population during medical treatment. The prevalence cohort was followed for two outcomes—complete seizure remission for ≥12 months and subsequent seizure relapse among those attaining a seizure remission. The study outcomes were estimated using Kaplan–Meier analysis. We found that the probability of attaining a ≥12 months of complete seizure freedom to be approximately 3–4% per year through 8 years of follow-up. By year 5 since the start of seizure remission, the cumulative probability of seizure relapse was 81%, although only half of the patients with seizure relapse went on to experience their previous seizure frequency. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09201211
- Volume :
- 93
- Issue :
- 2/3
- Database :
- Academic Search Index
- Journal :
- Epilepsy Research
- Publication Type :
- Academic Journal
- Accession number :
- 57682814
- Full Text :
- https://doi.org/10.1016/j.eplepsyres.2010.11.005