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Tandem allylic amination/ring-opening/oxa-Michael addition reactions of chromone-derived Morita–Baylis–Hillman acetates with amines

Authors :
Wu, Chen
Zeng, Hao
Liu, Li
Wang, Dong
Chen, Yongjun
Source :
Tetrahedron. Feb2011, Vol. 67 Issue 6, p1231-1237. 7p.
Publication Year :
2011

Abstract

Abstract: The reaction of chromone-derived Morita–Baylis–Hillman acetates with amines was developed via tandem allylic amination/chromone ring-opening/oxa-Michael addition to provide 2-substituted-3-aminomethy-lene-chromans in convenient and efficient way, and subsequent applied in the synthesis of benzopyranylpyrimidine compounds. Various amines exhibited different reactivities depending on their molecular structural characteristics. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00404020
Volume :
67
Issue :
6
Database :
Academic Search Index
Journal :
Tetrahedron
Publication Type :
Academic Journal
Accession number :
57511497
Full Text :
https://doi.org/10.1016/j.tet.2010.11.089