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Racial Differences in the Association Between Sex Hormone-Binding Globulin and Adiposity in Premenopausal Women.
- Source :
-
Diabetes Care . Oct2010, Vol. 33 Issue 10, p2274-2276. 3p. 1 Chart. - Publication Year :
- 2010
-
Abstract
- OBJECTIVE -- To assess the associations between measures of adiposity and sex hormone-binding globulin (SHBG) and to evaluate whether such associations differ by race. RESEARCH DESIGN AND METHODS -- Adiposity was measured by anthropometry and dual-energy X-ray absorptiometry among women (146 white, 50 black, and 25 Asian) aged 18-44 years in the BioCycle study. SHBG was repeatedly measured over one to two menstrual cycles. The ratio of trunkal to leg fat (T/L) was used to assess upper to lower body adiposity. RESULTS -- Among whites, all adiposity measures were significantly and inversely associated with SHBG. Among blacks, BMI (β = -0.032), waist circumference (β = -0.016), and T/L (β = -0.033) were significantly associated with SHBG, whereas total and trunkal fat were not (P interaction with race <0.04). Among Asians, measures of central and upper body fat were significantly associated with SHBG (e.g., T/L, β = -0.84) but not BMI. CONCLUSIONS-- Associations between SHBG and adiposity differ by race among premenopausal women. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01495992
- Volume :
- 33
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Diabetes Care
- Publication Type :
- Academic Journal
- Accession number :
- 56643536
- Full Text :
- https://doi.org/10.2337/dc10-0670