ENDOSCOPIC AND HISTOPATHOLGIC CORRELATIONS IN COLONIC CANCER.

Cancer of large bowel, colon and rectum is among the most frequent cancers in Western Europe. The diagnosis of colorectal cancer is possible mostly as a direct result of using videoendoscopy and having the possibility of taking colonic biopsies. To assess and correlate the endoscopic and histopathological parameters of malign colorectal tumors. 230 patient diagnosed at endoscopy with colonic tumors tumors between 2007 and 2009 in the Endoscopy Department of the 3rd Medical Clinic from Oradea were analyzed. We studied the epidemiological parameters, the morphologic features and the site of lesions identified during the endoscopy, as well as the histopathology characteristics using Dukes staging system (1940). From 2017 patients who underwent endoscopy, 203 (10%) were diagnosed with different histopathological types of colorectal cancer. The left colon was the most frequent localization (77%). Endoscopicaly, the polypoid-stenotic appearance was the most frequent (40.8%) type of cancer. In the majority of the cases we identified invasive carcinomas (88.2%) like intestinal adenocarcinoma (158 cases -77.8%) or „signet ring cells‟ carcinoma (12 cases -5.9%). The grading of the adenocarcinomas was assessed using the Grinnel scale: G-I: 97 cases, G-II: 48 cases, G-III: 13 cases. The frequency of colorectal cancer in western Romania is relatively high. The majority of the patients in our study had rectosigmoidian cancers. Most of them were polypoid-stenotic cancers and histologically, the adenocarcinoma was the most frequent form of colorectal cancer. [ABSTRACT FROM AUTHOR]