Back to Search Start Over

Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation.

Authors :
Derand, Renaud
Bulteau-Pignoux, Laurence
Mettey, Yvette
Zegarra-Moran, Olga
Howell, L. Daniel
Randak, Christoph
Galietta, Luis J.V.
Cohn, Jonathan A.
Norez, Caroline
Romio, Leila
Vierfond, Jean-Michel
Joffre, Michel
Becq, Frederic
Source :
American Journal of Physiology. Nov2001 Part 1 of 1, Vol. 281 Issue 5, pC1657. 10p. 1 Diagram, 1 Chart, 22 Graphs.
Publication Year :
2001

Abstract

Examines the use of adenosine triphosphatase (ATPase) activity and phosphorylation in the activation of G551D cystic fibrosis transmembrane conductance regulator (CFTR) channel with 5-butyl-6-hydroxy-10-chlorobenzo[c]quinolizinium chloride (MPB 91). Effect of MPB on ATPase; Development of CFTR modulators.

Details

Language :
English
ISSN :
00029513
Volume :
281
Issue :
5
Database :
Academic Search Index
Journal :
American Journal of Physiology
Publication Type :
Academic Journal
Accession number :
5591318