The biocompatibility of HA thin films deposition on anodized titanium alloys

Abstract: A thin hydroxyapatite (HA) film was deposited on anodized titanium for the biocompatibility by RF sputtering method. The anodized titanium has improved its bioactivity further by the HA deposition on the anodized titanium surface. TiO2 layer with 0.2~0.5μm diameter pore size was formed on the Ti surface by anodization. HA film deposited surface showed that the pore size and number decreased compared with non-HA deposited surface. The corrosion resistance of HA deposited/anodized Ti was higher than that of the non-treatment Ti alloy in Hank''s solution, indicating better protective effect. From the results of cell culture using MTT assays, the best cell proliferation showed in HA deposited surface after anodization of Ti surfaces compared with another surface treatment. [Copyright &y& Elsevier]