Oxidative stress-inducing potential of butachlor in a freshwater fish, Cyprinus carpio (L).

Oxidative stress-inducing potential of butachlor was studied in fresh water fish, Cyprinus carpio. Fish was exposed to butachlor (0.17 ppm in acetone) for a period of 24, 48, or 72 h. Various markers of oxidative stress, including catalase, glutathione S-transferase, glutathione reductase, levels of reduced glutathione (GSH) and lipid peroxidation (LPO), were estimated in liver, kidneys, and gills of fish. Butachlor-induced LPO and antioxidant enzyme activity and depleted levels of GSH in all organs examined. Fish exposed to butachlor experienced oxidative stress which was time dependent. The tissue antioxidants seemed to be induced in order to counteract the impact of free radicals, denoting an adaptation of fish to overcome chemical-induced stress. [ABSTRACT FROM AUTHOR]