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Design, synthesis and biotest of a bicyclo[3.3.1]nonane analogue of 2-amino-5,6-dihydro-4H-1,3-thiazine
- Source :
-
Mendeleev Communications . Nov2010, Vol. 20 Issue 6, p323-325. 3p. - Publication Year :
- 2010
-
Abstract
- To enhance the lipophilicity of the NO-synthase inhibitor 2-amino-5,6-dihydro-4H-1,3-thiazine, its bridgehead analogue was suggested on the basis of molecular modeling; the synthetic routes to new 3-thia-1-azabicyclo[3.3.1]nonane derivatives and the results of their biological testing are presented. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09599436
- Volume :
- 20
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Mendeleev Communications
- Publication Type :
- Academic Journal
- Accession number :
- 55504262
- Full Text :
- https://doi.org/10.1016/j.mencom.2010.11.007