Back to Search
Start Over
Pilot survey of commercial pasteurized milk consumed in the metropolitan area of Rio de Janeiro, Brazil, for tetracyclines residues, including the 4-epimers of oxytetracycline, tetracycline and chlortetracycline.
- Source :
-
Food Additives & Contaminants: Part B: Surveillance Communications . Dec2010, Vol. 3 Issue 4, p220-227. 8p. - Publication Year :
- 2010
-
Abstract
- This pilot survey aimed to assess the occurrence of tetracyclines and the 4-epimers of oxytetracycline, tetracycline and chlortetracycline in commercial pasteurized milks sold in the metropolitan area of Rio de Janeiro, Brazil, between October 2009 and March 2010. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, developed and validated in our laboratory, was used. All 100 analyzed samples were compliant, but 14 contained oxytetracycline in concentrations ranging from the method limit of detection (3.7 µg l-1) to the method limit of quantification (12.2 µg l-1). One sample contained oxytetracycline and tetracycline simultaneously (at a concentration slightly higher than method limit of quantification, 7.0 µg l-1). The presence of 4-epioxytetracycline and 4-epitetracycline in contaminated samples with the parent drugs could not be confirmed as traces were detected only in the quantification MRM transition. No other tetracyclines were detected. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19393210
- Volume :
- 3
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Food Additives & Contaminants: Part B: Surveillance Communications
- Publication Type :
- Academic Journal
- Accession number :
- 55474937
- Full Text :
- https://doi.org/10.1080/19393210.2010.531401