Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk.

Authors :: Vollrath, Douglas
Wei Feng
Duncan, Jacque L.
Yasumura, Douglas
D'Cruz, Patricia M.
Chappelow, Aimee
Matthes, Michael T.
Kay, Mark A.
LaVail, Matthew M.
Source :: Proceedings of the National Academy of Sciences of the United States of America. 10/23/2001, Vol. 98 Issue 22, p12584. 6p. 10 Diagrams, 2 Graphs.
Publication Year :: 2001
Abstract: Examines the effects of gene transfer of Mertk to Royal College of Surgeons (RCS) rat retina for the correction of retinal dystrophy phenotype. Selection of adenovirus as initial vector; Use of electroretinographic analysis; Importance of RCS rat as model for gene therapy.

Language :: English
ISSN :: 00278424
Volume :: 98
Issue :: 22
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 5537245
Full Text :: https://doi.org/10.1073/pnas.221364198

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