A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation

Authors :: Peters, Martin
Breinbauer, Rolf
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Dec2010, Vol. 51 Issue 50, p6622-6625. 4p.
Publication Year :: 2010
Abstract: Abstract: The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C–H activated borylation of arenes with its current scope and limitations are reported. [Copyright &y& Elsevier]

Subjects :: *ORGANIC synthesis
*ALKYLATION
*LIGANDS (Chemistry)
*CATALYSIS
*CARBENES
*HETEROCYCLIC compounds
*PYRIDINE

Language :: English
ISSN :: 00404039
Volume :: 51
Issue :: 50
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 55210181
Full Text :: https://doi.org/10.1016/j.tetlet.2010.10.059

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