Antihyperlipidemic and Antioxidant Activity of Methanolic Extract of Trianthema portulacastrum in Rats Fed a High-Fat Diet.

The methanolic extract of Trianthema portulacastrum (Aizoaceae) was evaluated for antihyperlipidemic and antioxidant activity in high-fat-diet-induced hyperlipidemic rats. It was found that the extract caused a significant reduction in the lipid levels in hyperlipidemic rats and was comparable with the standard anti-hyperlipidemic drug atorvastatin. It was also found that the plant extract increased the liver antioxidant enzyme (catalase, superoxide dismutase, glutathione) levels while reducing the lipid peroxide (malondialdehyde) levels. [ABSTRACT FROM AUTHOR]