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A practical solution-phase synthesis of an antagonistic peptide of TNF-α based on hydrophobic tag strategyElectronic supplementary information (ESI) available: Experimental details. See DOI: 10.1039/c0cc03090b.
- Source :
-
Chemical Communications . Nov2010, Vol. 46 Issue 43, p8219-8221. 3p. - Publication Year :
- 2010
-
Abstract
- A simple acid-resistanthydrophobic tag, which can be removed rapidly in a single-step procedure after overall peptide synthesis, has been developed to accomplish practical solution-phase synthesis of a 15-mer antagonistic peptide of TNF-α (A-TNF-α). Hydrophobically tagged peptides can be separated as precipitates at each step by addition of a polar organic solvent. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 46
- Issue :
- 43
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 54843015
- Full Text :
- https://doi.org/10.1039/c0cc03090b