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Upstream open reading frames: Molecular switches in (patho)physiology.
- Source :
-
BioEssays . Oct2010, Vol. 32 Issue 10, p885-893. 9p. 5 Diagrams. - Publication Year :
- 2010
-
Abstract
- The authors provide an overview of upstream open reading frame (uORF)-mediated translational control. They describe how aberrant uORF regulation can be translated into pathophysiology. They cite the role of contemporary sequencing technologies in addressing the implications of uORF-mediated translational control in human disease. The authors also conclude that uORF translation has pathophysiological significance.
Details
- Language :
- English
- ISSN :
- 02659247
- Volume :
- 32
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- BioEssays
- Publication Type :
- Academic Journal
- Accession number :
- 54490070
- Full Text :
- https://doi.org/10.1002/bies.201000037