Spiroborate catalyzed reductions with N,N-diethylaniline borane

Authors :: Coleridge, Brian M.
Angert, Thomas P.
Marks, Lucas R.
Hamilton, Patrick N.
Sutton, Christopher P.
Matos, Karl
Burkhardt, Elizabeth R.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Nov2010, Vol. 51 Issue 46, p5973-5976. 4p.
Publication Year :: 2010
Abstract: Abstract: Reduction of esters, amides, and ketones by N,N-diethylaniline borane is accelerated by catalysts derived from spiroborate complexes. Esters are reduced at ambient temperature in less than 4h with this amine borane and 5mol% spiroborate 6. Functional group selectivity shows ketone and tertiary amide reduction is faster than ester or nitrile reduction. [ABSTRACT FROM AUTHOR]

Subjects :: *CHEMICAL reduction
*DIETHYLANILINE
*CATALYSTS
*TEMPERATURE effect
*ESTERS
*FUNCTIONAL groups

Language :: English
ISSN :: 00404039
Volume :: 51
Issue :: 46
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 54482357
Full Text :: https://doi.org/10.1016/j.tetlet.2010.09.022