Air-Stable, Cationic, Lewis Acid, Titanocene Perfluorooctanesulfonate-Catalyzed Reductive Cleavage of S-S Bond by Zinc and Its Application in Synthesis of Thioesters.

Titanocene perfluorooctanesulfonate is air-stable complex. In the presence of 10 mol% of the complex, reductive cleavage of an S-S bond by zinc in commercial tetrahydrofuran at room temperature led to nucleophilic sulfur anion species, which reacted with acid anhydrides to afford thioesters in good to excellent yields. [ABSTRACT FROM AUTHOR]