Back to Search Start Over

Subclinical Hypothyroidism and the Risk of Coronary Heart Disease and Mortality.

Authors :
Rodondi, Nicolas
Den Elzen, Wendy P. J.
Bauer, Douglas C.
Cappola, Anne R.
Razvi, Salman
Walsh, John P.
Åsvold, Bjørn O.
Iervasi, Giorgio
Imaizumi, Misa
Collet, Tinh-Hai
Bremner, Alexandra
Maisonneuve, Patrick
Sgarbi, José A.
Khaw, Kay-Tee
Vanderpump, Mark P. J.
Newman, Anne B.
Cornuz, Jacques
Franklyn, Jayne A.
Westendorp, Rudi G. J.
Vittinghoff, Eric
Source :
JAMA: Journal of the American Medical Association. 9/22/2010, Vol. 304 Issue 12, p1365-1374. 10p. 3 Charts, 2 Graphs.
Publication Year :
2010

Abstract

The article focuses on a study which examined the risks of coronary heart disease (CHD) and total mortality among adults with subclinical hypothyroidism. The study included 55,287 adults in the U.S., Europe, Australia, Brazil and Japan, who were followed up from 1972 to 2007. Of the total study participants, 3,450 developed subclinical hypothyroidism, while 51,837 had euthyroidism. Study authors found that increased thyroid-stimulating hormone (TSH) concentration increased the risk of CHD and CHD-related mortality. They concluded that patients with subclinical hypothyroidism have higher risk of CHD.

Details

Language :
English
ISSN :
00987484
Volume :
304
Issue :
12
Database :
Academic Search Index
Journal :
JAMA: Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
53917331
Full Text :
https://doi.org/10.1001/jama.2010.1361