Fármaco-terapéutica de la sepsis: ¡un proceso frustrante y un gran desafío!

Sepsis ranks first among causes of death in intensive care units, which is why their understanding has been the subject of several studies. This condition is a medical challenge because its diagnostic criteria have never been able to reach a consensus, thus hindering their therapeutic approach. The overview of its pathophysiology has not been different, until recent years was understood that sepsis is a close relationship between the infectious agent and immune system involvement, particularly in each host, which prompted the use of different drugs that target to counteract this response, sometimes contradictory results obtained. All this comes together in one big puzzle of knowledge that has gradually been deciphered, awaiting further research to continue with further progress in the drug-treatment of sepsis. [ABSTRACT FROM AUTHOR]