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Role of Innate Immunity in Helicobacter pylon-Induced Gastric Malignancy.

Authors :
Peek Jr., Richard M.
Fiske, Chris
Wilson, Keith T.
Source :
Physiological Reviews. Jul2010, Vol. 90 Issue 3, p831-858. 28p.
Publication Year :
2010

Abstract

The article offers information on the role played in the Helicobacter pylori-induced gastric malignancy of natural immunity in the gastric niche. It mentions that the dysregulation of H. pylori of the innate immune response lead to the development of gastric cancer and peptic ulceration. It states various factors that stand as barrier for the colonization of the stomach which are prevail by H. pylori over including peristalsis, gastric acidity, and the host immune system.

Details

Language :
English
ISSN :
00319333
Volume :
90
Issue :
3
Database :
Academic Search Index
Journal :
Physiological Reviews
Publication Type :
Academic Journal
Accession number :
53484727
Full Text :
https://doi.org/10.1152/physrev.00039.2009