Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement.

Authors :: Feng Liu
Verin, Alexander D.
Borbiev, Talai
Garcia, Joe G.N.
Source :: American Journal of Physiology. Jun2001 Part 1 of 2, Vol. 280 Issue 6, pL1309. 9p. 7 Color Photographs, 8 Black and White Photographs, 4 Graphs.
Publication Year :: 2001
Abstract: Investigates the impact of the cyclic adenylic acid-dependent protein kinase A (cAMP/PKA) inhibitors, Rp diastereomer of adenosine 3'-5'-cyclic monophosphorothioate and PKA inhibitor, on bovine pulmonary artery and lung microvascular endothelial cell cytoskeleton reorganization. Involvement of significant activity between cAMP- and extracellular signal-regulated kinase-dependent signaling pathways.

Subjects :: *PROTEIN kinases
*LUNGS
*PULMONARY artery
*VASCULAR endothelium
*CHEMICAL inhibitors
*PHYSIOLOGY
*CYTOCHEMISTRY

Tools