Expansion of CD8+/perforin+ effector memory T cells in the bone marrow of patients with thymoma-associated pure red cell aplasia.

The article offers information about pure red cell aplasia (PRCA). It mentions that PRCA is represented by normochronic normocytic anemia, reticulocytopenia, and severe erythroid hypoplasia of the bone marrow along with clonal T-cell expansion in the bone marrow or peripheral blood. It further present case studies of several patients including some with PRCA and with thymoma, some with PRCA and myelodysplastic syndrome and some with PRCA and follicular lymphoma.