Kinetics of base hydrolysis of α-amino acid esters catalyzed by [Pd(Et4en)(H2O)2]2+.

The kinetics of base hydrolysis of amino acid esters, glycine-, histidine-, and methionine methyl esters in the presence of [Pd(Et4en))(H2O)2]2+ is studied in aqueous solution at 25°C and I = 0.1 mol dm-1 (Et4en = N,N,N',N'-tetraethylethylenediamine). The rate of ester hydrolysis for glycine methyl ester is studied at different temperatures and dioxane-water solutions of different compositions. The kinetic data fit a model which assumes that hydrolysis proceeds in one step. Hydrolysis of the esters is catalyzed by [Pd(Et4en)(H2O)2]2+ with catalysis ratio values of 2.5 × 104, 3.15, and 7.43 for glycine-, histidine-, and methionine methyl esters, respectively. Activation parameters for the base hydrolysis are evaluated. [ABSTRACT FROM AUTHOR]