Survival rate of H5N1 highly pathogenic avian influenza viruses at different temperatures.

The survival rate of Korean H5N1 highly pathogenic avian influenza (HPAI) viruses was inves- tigated at different temperatures under the laboratory conditions. The estimated survival days for a starting viral concentration of 106.5 50% egg infectious dose/0.1 mL were 930, 1,042, and 3,213 d at 4°C; 226, 232, and 293 d at 20°C; and 51, 55, and 58 d at 30°C for A/ chicken/Korea/ES/03, A/chicken/Korea/IS /06, and A/chicken/Korea/Cimje/08 (Gimje/08) viruses, re- spectively. The stability of the Gimje/08 virus was sta- tistically significant compared with the other 2 viruses except for the data between Gimje/08 and A/chicken/ Korea/IS/06 virus at 30°C. This result indicated that the survival rate of 3 Korean HPAJ viruses is different at various temperatures, which might have partially in- fluenced the large scale of HPAI outbreak in Korea in 2008. [ABSTRACT FROM AUTHOR]