CuCl-catalyzed cycloaddition of 1,3-butadiynes with primary amines: an atom-economic process for synthesis of 1,2,5-trisubsituted pyrroles

Authors :: Zheng, Qingwei
Hua, Ruimao
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Aug2010, Vol. 51 Issue 34, p4512-4514. 3p.
Publication Year :: 2010
Abstract: Abstract: 1,3-Butadiynes underwent inter- and intramolecular double hydroamination with primary amines in the presence of CuCl at 100°C to afford 1,2,5-trisubsituted pyrroles in good to high yields. [Copyright &y& Elsevier]

Subjects :: *CUPROUS chloride
*CATALYSTS
*RING formation (Chemistry)
*ACETYLENE
*PYRROLES
*AMINATION
*AMINES
*ORGANIC synthesis

Language :: English
ISSN :: 00404039
Volume :: 51
Issue :: 34
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 52484574
Full Text :: https://doi.org/10.1016/j.tetlet.2010.06.092

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