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Loss of p16[sup Ink4a] confers susceptibility to metastatic melanoma in mice.

Authors :
Krimpenfort, Paul
Quon, Kim C.
Mooi, Wolter J.
Loonstra, Ate
Berns, Anton
Source :
Nature. 9/6/2001, Vol. 413 Issue 6851, p83. 4p. 6 Color Photographs, 6 Diagrams, 2 Charts, 5 Graphs.
Publication Year :
2001

Abstract

Demonstrates that mice do not show a significant predisposition to spontaneous melanoma tumor formation after the loss of a genetic factor. Proliferation of embryo fibroblast; Mild phenotype implying the loss of genetic material.

Subjects

Subjects :
*MELANOMA
*GENETICS
TUMOR genetics

Details

Language :
English
ISSN :
00280836
Volume :
413
Issue :
6851
Database :
Academic Search Index
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
5214055
Full Text :
https://doi.org/10.1038/35092584