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Distinctive Expression of the Polycomb Group Proteins Bmi1 Polycomb Ring Finger Oncogene and Enhancer of Zeste Homolog 2 in Nonsmall Cell Lung Cancers and Their Clinical and Clinicopathologic Significance.

Authors :
Kikuchi, Junko
Kinoshita, Ichiro
Shimizu, Yasushi
Kikuchi, Eiki
Konishi, Jun
Oizumi, Satoshi
Kaga, Kichizo
Matsuno, Yoshihiro
Nishimura, Masaharu
Dosaka-Akita, Hirotoshi
Source :
Cancer (0008543X). 6/15/2010, Vol. 116 Issue 12, p3015-3024. 10p. 1 Diagram, 5 Charts, 2 Graphs.
Publication Year :
2010

Abstract

The article provides information on a study which assessed Bmil polycomb ring finger oncogene (Bmil) and enhancer of zeste homolog 2 (EZH2) protein expression in specimens of human nonsmall cell lung cancer (NSCLC). The study also investigated the association between Bmil and EZH2 proteins and several features, such as clinical and clinicopathologic parameters, cell biologic characteristics and patient outcomes. A detailed discussion the findings is presented.

Details

Language :
English
ISSN :
0008543X
Volume :
116
Issue :
12
Database :
Academic Search Index
Journal :
Cancer (0008543X)
Publication Type :
Academic Journal
Accession number :
51859949
Full Text :
https://doi.org/10.1002/cncr.25128