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Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer.
- Source :
-
Annals of Oncology . Apr2010, Vol. 21 Issue 4, p766-771. 6p. 4 Charts, 2 Graphs. - Publication Year :
- 2010
-
Abstract
- Background: S-1, a novel oral fluoropyrimidine, is well tolerated in patients with metastatic colorectal cancer (mCRC). The response rate of S-1 for colorectal cancer is high, ranging from 35% to 40%. This study aimed to evaluate the safety and efficacy of S-1 combined with oral leucovorin (LV) to enhance antitumor activity in chemotherapy-naive patients with mCRC. [ABSTRACT FROM PUBLISHER]
- Subjects :
- *FOLINIC acid
*COLON cancer
*FLUOROPYRIMIDINES
*METASTASIS
*DRUG efficacy
Subjects
Details
- Language :
- English
- ISSN :
- 09237534
- Volume :
- 21
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Annals of Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 51493419
- Full Text :
- https://doi.org/10.1093/annonc/mdp371