TRATAMENTUL HEPATITEI ACUTE VIRALE C HVC treatment.

Acute hepatitis C is an insufficient studied disease because unspecific clinical manifestations, diagnostic difficulties and limited epidemiological data. High rate of development of chronic C hepatitis, rapid progression to cirrhosis and hepatocellular carcinoma are sufficient arguments for an early treatment of acute hepatitis C. Interferon treatment of acute hepatitis C is highly efficient, fact proved by the SVR (sustained virological response) up to 94-98% in the studies of patients treated with conventional interferon or pegylated interferons. The absence of a standard therapy lead to necessity to analyse all this studies and to elaborate several treatment recommendations. The available data at this moment points to a therapy with pegylated interferon alpha-2a or alpha-2b, with 12-24 weeks duration, initiated in the first 12 weeks after acute onset of hepatitis. [ABSTRACT FROM AUTHOR]