Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus.

Authors :: Drexler, Jan Felix
Helmer, Angelika
Kirberg, Heike
Reber, Ulrike
Panning, Marcus
Müller, Marcel
Höfling, Katja
Matz, Bertfried
Drosten, Christian
Eis-Hübinger, Anna Maria
Source :: Romanian Journal of Infectious Diseases / Revista Romana de de Boli Infectioase. 2009, Vol. 12 Issue 3, p189-191. 3p. 1 Graph.
Publication Year :: 2009
Abstract: Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic. [ABSTRACT FROM AUTHOR]

Subjects :: *H1N1 influenza
*RNA
*REVERSE transcriptase polymerase chain reaction
*RAPID methods (Microbiology)

Language :: English
ISSN :: 14543389
Volume :: 12
Issue :: 3
Database :: Academic Search Index
Journal :: Romanian Journal of Infectious Diseases / Revista Romana de de Boli Infectioase
Publication Type :: Academic Journal
Accession number :: 51336845
Full Text :: https://doi.org/10.3201/eid1510.091186

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