The association between previous statin use and development of atrial fibrillation in patients presenting with acute coronary syndrome

Abstract: Aims: To examine the association between statin use and the development of atrial fibrillation (AF) in patients presenting with acute coronary syndrome (ACS). Methods: From a total of 1000 patients presenting with ACS 241 were on and 759 were not on statin. An AF episode was accepted as endpoint. Results: The incidence of AF was less frequent in statin group compared to non-statin group (5% vs 10%, respectively, p =0.01). Independent predictors of AF were left atrial diameter, use of statin, age, hypertension, previous AF and use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers. Conclusions: In ACS patients, statin treatment was associated with lower incidence of AF. [Copyright &y& Elsevier]