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Increased neuronal excitability and seizures in the Na[sup +]/H[sup +] exchanger null...

Authors :
Gu, Xiang Q.
Hang Yao
Haddad, Gabriel G.
Source :
American Journal of Physiology: Cell Physiology. Aug2001, Vol. 281 Issue 2, pC496. 8p. 8 Diagrams, 9 Graphs.
Publication Year :
2001

Abstract

Demonstrates the existence of an important functional interaction between the sodium/hydrogen exchanger isoform 1 (NHE1) protein and the voltage-sensitive sodium channel in mice. Manifestation of neurological diseases; Hippocampal neuron functioning; Mechanisms for increased excitability in mutant NHE1 neurons; Interaction disturbance of specific proteins in neuron membrane.

Details

Language :
English
ISSN :
03636143
Volume :
281
Issue :
2
Database :
Academic Search Index
Journal :
American Journal of Physiology: Cell Physiology
Publication Type :
Academic Journal
Accession number :
5008886
Full Text :
https://doi.org/10.1152/ajpcell.2001.281.2.C496