Phenserine regulates translation of beta-amyloid precursor protein mRNA by a putative....

Authors :: Shaw, Karen T.Y.
Utsuki, Tadanobu
Rogers, Jack
Qian-Sheng Yu
Sambamurti, Kumar
Brossi, Arnold
Yuan-Wen Ge
Lahiri, Debomoy K.
Greig, Nigel H.
Source :: Proceedings of the National Academy of Sciences of the United States of America. 06/19/2001, Vol. 98 Issue 13, p7605. 6p. 5 Diagrams, 4 Graphs.
Publication Year :: 2001
Abstract: Examines the mechanism of phenserine actions to define the regulatory elements in beta-amyloid precursor protein processing (betaAPP). Effect of phenserine to betaAPP and amyloid-betapeptide (Abeta) levels in neuroblastoma cells; Regulation of betaAPP expression to reduce Abeta.

Subjects :: *PROTEIN precursors
*AMYLOID beta-protein precursor
*NEUROBLASTOMA
*THERAPEUTICS

Language :: English
ISSN :: 00278424
Volume :: 98
Issue :: 13
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 4934036
Full Text :: https://doi.org/10.1073/pnas.131152998

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