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5-Aminolevulinic Acid Is a Promising Marker for Detection of Anaplastic Foci in Diffusely Infiltrating Gliomas With Nonsignificant Contrast Enhancement.

Authors :
Widhalm, Georg
Wolfsberger, Stefan
Minchev, Georgi
Woehrer, Adelheid
Krssak, Martin
Czech, Thomas
Prayer, Daniela
Asenbaum, Susanne
Hainfellner, Johannes A.
Knosp, Engelbert
Source :
Cancer (0008543X). 3/15/2010, Vol. 116 Issue 6, p1545-1552. 8p.
Publication Year :
2010

Abstract

The article reports on the study which aims to clarify the efficacy of 5-Aminolevulinic Acid (5-ALA) in detecting the anaplastic foci in diffusely infiltrating gliomas with nonsignificant contrast enhancement. It notes that the 5-ALA is a promising marker that ensures the accuracy of tissue sampling for primary brain tumors. It implies that the 5-ALA is capable of optimizing the allocation of adjuvant treatments to patients due to its unaffected intraoperative brain shift.

Details

Language :
English
ISSN :
0008543X
Volume :
116
Issue :
6
Database :
Academic Search Index
Journal :
Cancer (0008543X)
Publication Type :
Academic Journal
Accession number :
48682325
Full Text :
https://doi.org/10.1002/cncr.24903