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A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain...

Authors :
Giordano, Frank J.
Gerber, Hans-Peter
Williams, Simon-Peter
VanBruggen, Nicholas
Bunting, Stuart
Ruiz-Lozano, Pilar
Yusu Gu
Nath, Anjali K.
Yan Huang
Hickey, Reed
Dalton, Nancy
Peterson, Kirk L.
Ross Jr., John
Chien, Kenneth R.
Ferrara, Napoleone
Source :
Proceedings of the National Academy of Sciences of the United States of America. 05/08/2001, Vol. 98 Issue 10, p5780. 6p. 4 Color Photographs, 4 Black and White Photographs, 2 Diagrams, 1 Chart, 13 Graphs.
Publication Year :
2001

Abstract

Studies the role of the cardiac myocyte as a mediator of paracrine signaling in the heart. Generation of cmVEGF-Null mice; Ventricular thinning, dilation and diminished contractile function in cmVEGF-Null hearts.

Details

Language :
English
ISSN :
00278424
Volume :
98
Issue :
10
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
4857379
Full Text :
https://doi.org/10.1073/pnas.091415198