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Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal...

Authors :
Saffery, Richard
Wong, Lee H.
Irvine, Danielle V.
Bateman, Melissa A.
Griffiths, Belinda
Cutts, Suzanne M.
Cancilla, Michael R.
Cendron, Angela C.
Stafford, Angela J.
Andy Choo, K.H.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 05/08/2001, Vol. 98 Issue 10, p5705. 6p. 2 Color Photographs, 1 Black and White Photograph, 4 Diagrams, 1 Graph.
Publication Year :
2001

Abstract

Reports on the construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation. Cell culture and transfection; Microcell-mediated chromosome transfer; In vitro approaches for artificial chromosome construction; Mardel(10) tagging and transfer into HT1080 cells.

Subjects

Subjects :
*HUMAN chromosomes
*TELOMERES

Details

Language :
English
ISSN :
00278424
Volume :
98
Issue :
10
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
4857364
Full Text :
https://doi.org/10.1073/pnas.091468498