Back to Search Start Over

Cholesterol Modification of Sonic Hedgehog Is Required for Long-Range Signaling Activity and....

Authors :
Lewis, Paula M.
Dunn, Matthew P.
McMahon, Jill A.
Logan, Malcolm
Martin, James F.
St-Jacques, Benoit
McMahon, Andrew P.
Source :
Cell. 06/01/2001, Vol. 105 Issue 5, p599. 14p. 15 Color Photographs, 33 Diagrams.
Publication Year :
2001

Abstract

Investigates the importance of cholesterol modification of sonic hedgehog for long-range signaling activity and effective modulation of signaling. Determinants of anterior-posterior polarity in the vertebrate limb field; Role of lipophilic modification in patterning of mouse digits.

Details

Language :
English
ISSN :
00928674
Volume :
105
Issue :
5
Database :
Academic Search Index
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
4827714
Full Text :
https://doi.org/10.1016/S0092-8674(01)00369-5