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Executive function (capacity for behavioral self-regulation) and decline predicted mortality in a longitudinal study in Southern Colorado
- Source :
-
Journal of Clinical Epidemiology . Mar2010, Vol. 63 Issue 3, p307-314. 8p. - Publication Year :
- 2010
-
Abstract
- <bold>Objective: </bold>To assess the relationship between mortality and impairment and decline in a specific executive cognitive function, the capacity for behavioral self-regulation.<bold>Study Design and Setting: </bold>This study examined the association between mortality and baseline and 22-month decline in the capacity for behavioral self-regulation, as measured by the Behavioral Dyscontrol Scale, among 1,293 participants of the San Luis Valley Health and Aging Study (SLVHAS), a population-based longitudinal study. The Behavioral Dyscontrol Scale and a measure of overall mental status, the Mini-Mental State Examination, were administered at baseline and follow-up interviews. Cox regression was used to examine baseline and decline in capacity for behavioral self-regulation as possible predictors of mortality.<bold>Results: </bold>Baseline Behavioral Dyscontrol Scale score was predictive of mortality, independent of demographics and comorbidity count (hazard ratio [HR]=1.07; 95% confidence interval [CI]: 1.04, 1.09). It remained a significant predictor with further adjustment for Mini-Mental State Examination score. Decline in this specific executive cognitive function was associated with mortality after adjustment for covariates and baseline cognitive scores (HR=1.09; 95% CI: 1.04, 1.13).<bold>Conclusion: </bold>Thus, both baseline capacity for behavioral self-regulation and its decline over time predicted mortality in the SLVHAS cohort. These associations may partly be attributed to maintaining the ability for self-care. Understanding how specific forms of impairment contribute to mortality may help identify patients who could benefit from early intervention. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08954356
- Volume :
- 63
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Clinical Epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 47955867
- Full Text :
- https://doi.org/10.1016/j.jclinepi.2009.06.004