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Zoonotic aspects of rotaviruses
- Source :
-
Veterinary Microbiology . Jan2010, Vol. 140 Issue 3/4, p246-255. 10p. - Publication Year :
- 2010
-
Abstract
- Abstract: Rotaviruses are important enteric pathogens of humans and animals. Group A rotaviruses (GARVs) account for up to 1 million children deaths each year, chiefly in developing countries and human vaccines are now available in many countries. Rotavirus-associated enteritis is a major problem in livestock animals, notably in young calves and piglets. Early in the epidemiological GARV studies in humans, either sporadic cases or epidemics by atypical, animal-like GARV strains were described. Complete genome sequencing of human and animal GARV strains has revealed a striking genetic heterogeneity in the 11 double stranded RNA segments across different rotavirus strains and has provided evidence for frequent intersections between the evolution of human and animal rotaviruses, as a result of multiple, repeated events of interspecies transmission and subsequent adaptation. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 03781135
- Volume :
- 140
- Issue :
- 3/4
- Database :
- Academic Search Index
- Journal :
- Veterinary Microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 47610169
- Full Text :
- https://doi.org/10.1016/j.vetmic.2009.08.028