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Pregnancy outcome after magnetic resonance–guided focused ultrasound surgery (MRgFUS) for conservative treatment of uterine fibroids
- Source :
-
Fertility & Sterility . Jan2010, Vol. 93 Issue 1, p199-209. 11p. - Publication Year :
- 2010
-
Abstract
- Objective: To report all pregnancies to date after magnetic resonance–guided focused ultrasound surgery (MRgFUS) for the conservative treatment of clinically significant uterine fibroids. Design: Prospective registry of all known pregnancies occurring after MRgFUS maintained by the device manufacturer and reported to the Food and Drug Administration. Setting: World experience of pregnancies after treatment with reports from 13 sites in seven countries. Patient(s): Fifty-one reproductive-age women with uterine leiomyomas. Intervention(s): Women underwent MRgFUS treatment for symptomatic uterine leiomyomas before this report. Main Outcome Measure(s): Pregnancy outcomes and complications. Result(s): Fifty-four pregnancies in 51 women have occurred after MRgFUS treatment of uterine leiomyomas. The mean time to conception was 8 months after treatment. Live births occurred in 41% of pregnancies, with a 28% spontaneous abortion rate, an 11% rate of elective pregnancy termination, and 11 (20%) ongoing pregnancies beyond 20 gestational weeks. The mean birth weight was 3.3 kg, and the vaginal delivery rate was 64%. Conclusion(s): Preliminary pregnancy experience after MRgFUS is encouraging, with a high rate of delivered and ongoing pregnancies. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00150282
- Volume :
- 93
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Fertility & Sterility
- Publication Type :
- Academic Journal
- Accession number :
- 47384109
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2008.10.001