Conformations of a model protein revealed by an aggregating CuIIporphyrin: sensing the differenceThis paper is dedicated in memory of Prof. Raffaello Romeo.Electronic supplementary information (ESI) available: Experimental details; spectral changes on increasing Tfor t-CuP; spectra of t-CuP in MilliQ water or buffers; CD spectra for t-CuP/PGA on increasing pH; RLS spectra corresponding to Fig. 4. See DOI: 10.1039/b918433c

Aggregated t-CuP binds to poly-l-glutamate through supramolecular interactions, revealing itself to be an extremely sensitive probe for the major conformations of the polymeric scaffold. [ABSTRACT FROM AUTHOR]