Factors influencing lopinavir and atazanavir plasma concentration.

Authors :: Stöhr, Wolfgang
Back, David
Dunn, David
Sabin, Caroline
Winston, Alan
Gilson, Richard
Pillay, Deenan
Hill, Teresa
Ainsworth, Jonathan
Gazzard, Brian
Leen, Clifford
Bansi, Loveleen
Fisher, Martin
Orkin, Chloe
Anderson, Jane
Johnson, Margaret
Easterbrook, Philippa
Gibbons, Sara
Khoo, Saye
Source :: Journal of Antimicrobial Chemotherapy (JAC). Jan2010, Vol. 65 Issue 1, p129-137. 9p. 3 Charts, 1 Graph.
Publication Year :: 2010
Abstract: Background: The protease inhibitors lopinavir and atazanavir are both recommended for treatment of HIV-infected patients. Considerable inter-individual variability in plasma concentration has been observed for both drugs. The aim of this study was to evaluate which demographic factors and concomitant drugs are associated with lopinavir and atazanavir plasma concentration. [ABSTRACT FROM PUBLISHER]