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Addition of allyl bromide to phenylacetylene catalyzed by palladium on alumina and its application to a continuous flow synthesis.

Authors :
Fukuyama, Takahide
Kippo, Takashi
Ryu, Ilhyong
Sagae, Takahiro
Source :
Research on Chemical Intermediates. 2009, Vol. 35 Issue 8/9, p1053-1057. 5p. 2 Diagrams, 1 Chart.
Publication Year :
2009

Abstract

The reaction of allyl bromide with phenylacetylene catalyzed by Pd/Al2O3 pellets and Pd/C powder was investigated. Bromoallylation of phenylacetylene took place to give a regioisomeric mixture of 1-bromo-substituted 1,4-dienes. The bromoallylation of phenylacetylene was successfully applied to a continuous flow synthesis using a stainless steel made column packed with Pd/Al2O3 pellets. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09226168
Volume :
35
Issue :
8/9
Database :
Academic Search Index
Journal :
Research on Chemical Intermediates
Publication Type :
Academic Journal
Accession number :
47010684
Full Text :
https://doi.org/10.1007/s11164-009-0069-x