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A highly polymorphic CA repeat marker at the human tumor necrosis factor alpha (TNFAα) locus.
- Source :
-
Journal of Human Genetics . 1998, Vol. 43 Issue 4, p278. 2p. - Publication Year :
- 1998
-
Abstract
- Abstract Tumor necrosis factor alpha (TNF alpha) in activated monocytes exerts cytotoxic activity and has a variety of other biological effects. We isolated a polymorphic dinucleotide (CA) repeat sequence from a genomic clone containing the gene located at 6p21.3. High heterozygosity (0.80) makes this polymorphism a useful marker in the genetic study of disorders affecting immunological response and cell differentiation. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TUMOR necrosis factors
*MONOCYTES
*GENES
*CELL differentiation
Subjects
Details
- Language :
- English
- ISSN :
- 14345161
- Volume :
- 43
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Human Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 4688258
- Full Text :
- https://doi.org/10.1007/s100380050090