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A Case-Control Study to Evaluate the Effectiveness of Mass Neonatal BCG Vaccination among Canadian Indians.
- Source :
-
American Journal of Public Health . Jul1986, Vol. 76 Issue 7, p783-786. 4p. - Publication Year :
- 1986
-
Abstract
- Abstract: This paper reports a case-control study to assess the protective effect of BCG (bacille Calmette-Guerin) vaccination among Indian infants in Manitoba, Canada. A record of past BCG vaccination was found in 49 per ¢ of the tuberculosis cases, compared to 77 per ¢ of the controls, yielding a relative risk of 0.30. Stratified analysis, controlling for age, increased the relative risk to 0.39 (95% confidence interval 0.22 - 0.69). The preventive fraction was 44 per ¢. Non-differential misclassification of exposure status could have occurred; if this was adjusted for, the relative risk would be reduced. If only bacteriologically confirmed cases were analyzed, the age-adjusted relative risk was 0.27. The protective effect of BCG vaccination in the newborn among Manitoba Indians is therefore at least 60 per ¢. The implications for health policy in this population are further discussed. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00900036
- Volume :
- 76
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- American Journal of Public Health
- Publication Type :
- Academic Journal
- Accession number :
- 4687449
- Full Text :
- https://doi.org/10.2105/AJPH.76.7.783