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Combination Therapy With Rituximab and Intravenous or Oral Fludarabine in the First-Line, Systemic Treatment of Patients With Extranodal Marginal Zone B-cell Lymphoma of the Mucosa-Associated Lymphoid Tissue Type.

Authors :
Salar, Antonio
Domingo-Domenech, Eva
Estany, Cristina
Canales, Miguel A.
Gallardo, Fernando
Servitje, Octavio
Fraile, Guadalupe
Montalbán, Carlos
Source :
Cancer (0008543X). 11/15/2009, Vol. 115 Issue 22, p5210-5217. 8p. 4 Charts.
Publication Year :
2009

Abstract

The article presents a study which examines the role of rituximab and fludarabine in treating extranodal marginal zone lymphomas of the mucosa-associated lymphoid tissue (MALT) type. It notes that patients with de novo extranodal MALT lymphoma received 375 mg/m² rituximab and 25 mg/m² fludarabine for four to six cycles. Results show that 62% of the participants achieved a complete remission (CR) while 38% achieved a partial remission (PR) after the third cycle.

Details

Language :
English
ISSN :
0008543X
Volume :
115
Issue :
22
Database :
Academic Search Index
Journal :
Cancer (0008543X)
Publication Type :
Academic Journal
Accession number :
45539098
Full Text :
https://doi.org/10.1002/cncr.24605