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Origin of the Mutations in the parkin Gene in Europe: Exon Rearrangements Are Independent Recurrent Events, whereas Point Mutations May Result from Founder Effects.

Authors :
Periquet, Magali
Lucking, Christoph B.
Vaughan, Jenny R.
Bonifati, Vincenzo
Durr, Alexandra
De Michele, Giuseppe
Horstink, Martin W.
Farrer, Matt
Illarioshkin, Sergei N.
Pollak, Pierre
Borg, Michel
Brefel-Courbon, Christine
Denefle, Patrice
Meco, Giuseppe
Gasser, Thomas
Breteler, Monique M. B.
Wood, Nick W.
Agid, Yves
Brice, Alexis
Source :
American Journal of Human Genetics. Mar2001, Vol. 68 Issue 3, p617. 10p. 1 Diagram.
Publication Year :
2001

Abstract

Presents information on a study which examined the origin of the mutations in the parkin gene among families and patients with early onset Parkinsonism in Europe. Methodology; Results and discussion.

Details

Language :
English
ISSN :
00029297
Volume :
68
Issue :
3
Database :
Academic Search Index
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
4486854
Full Text :
https://doi.org/10.1086/318791