Scalarane Sesterterpenes from the Chinese Sponge Phyllospongia foliascens.

Three new scalarane sesterterpenes, phyllofolactone L 1, phyllofenone D 2 and phyllofenone E 3, were isolated from the acetone extract of the South China Sea sponge Phyllospongia foliascens.Their structures were elucidated on the basis of spectroscopic analysis. Phyllofenone D 2 was cytotoxic against the P388 leukemia cell line with an IC50value of 6.5μgml. [ABSTRACT FROM AUTHOR]